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GPCRs

Our offerings:

50 GPCRs in place so far, 45 stable cell lines

Orphans
Class A Orphan receptorsGPR65
GPR68
GPR84
MRGPRX2
MRGPRB2 (mouse ortholog)
GPR18, GPR55 and GPR119GPR119
Neuron system related
Melanocortin receptorsMC1
MC2
MC3
MC4
MC5
5-Hydroxytryptamine receptors (Serotonin)5-HT1A
5-HT2A
5-HT2B
5-HT2C
Acetylcholine receptors (muscarinic)M1
M2
Opioid receptorsMOP
DOP
Orexin receptorsOX1R
OX2R
Dopamine receptorsD1R
Adenosine receptorsA2A
Histamine receptorsH1
Metabolism and hormone related
Glucagon receptor familyGLP1R
GIPR
GCGR
GLP2R
mGLP1R
Gonadotrophin-releasing hormone receptorsGnRHR
VIP and PACAP receptorsPAC1 (PACAP)
Ghrelin receptorGhrelin/GHSR-1a
Somatostatin receptorsSSTR2
Calcitonin receptorsCGRP receptor
Free fatty acid receptorsFFA1 (GPR40)
Bile acid receptorGPBA receptor (TGR5)
Immune system and cancer related
Chemokine receptorsCXCR1/IL-8a
CXCR2/IL-8b
CXCR3
CXCR4
CXCR5
CXCR6
CX3CR1
CXCR7/ACKR3
Anaphylatoxin receptors (Complement peptide receptors)C3aR
C5aR1
Apelin receptorAPJ (apelin)
Lysophospholipid (LPA) receptorsLPA1
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