Biologics-BioDuro-Sundia

Biologics

Technologies optimized for best support of discovery and development of biologics products.

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Biologics

Technologies optimized for best support of discovery and development of biologics products.

Overview

BioDuro-Sundia has built up comprehensive antibody discovery capabilities with differentiation from current market offerings. Multiple technologies are established to discover antibodies from all kinds of antibody gene sources, including immunized animals, human patients, and synthetic DNA. We use creative strategies to overcome the pain points of the therapeutic antibody discovery field with a goal to generate antibodies for not only the regular drug targets but also the challenging ones, such as GPCRs, ion channels and even intracellular targets. We are establishing a cutting-edge antibody discovery platform with unique strengths and capabilities that will meet the needs of current and future therapeutic antibody discovery and optimization for clients around the world.

Highlight

Advanced immunization technologies to generate antibodies for difficult to purify and challenging antigens

Efficient clone retrieval, resulting in higher quality antibody ‘hits’ in a shorter time

Biomarker discovery assays performed in non-human primates to provide real-life results

Advanced therapeutic protein characterization techniques including Thermal/Colloidal characterization, Intact mass analysis, Peptide mapping, Glyco-protein profiling, Charge of variants and Bind affinity

Exhaustive PK/PD services: wide range of animal species, tailored sampling, diverse analytical platforms, specialized biologics products

Flexible business models with custom service packages or collaborative projects

A Biologics team of over 40 scientists with expertise covering antibody discovery, cancer immunotherapy, biophysics, pharmacology, and protein science

Core Competencies

Antibody discovery based on synthetic/immune library, hybridoma, single B cell technology

Antibody production

Antibody binding characterization (Biacore 8K,Octet RED 384)

Antibody stability characterization (Uncle)

In vitro/in vivo functional assays

Specialized Equipment

Gyrolab xPLore™/ Automated Immunoassays

Triple Quad 6500+ System

Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer

Biacore 8K surface plasmon resonance (SPR) system

UNCLE, all-in-one biologics stability screening platform

ECM 2001+ electrofusion and electroporation system

Chemistry

Medicinal Chemistry Computational Chemistry Synthetic Chemistry Analytical Chemistry Scale Up Chemistry

DMPK

In Vivo PK and TK In Vitro ADME Bioanalytical Service Exploratory Toxicity In Rodents, Dogs and Monkeys Large Molecules Capabilities Bioanalytical Instruments

Discovery Biology

Biochemical Assays Cellular Assays Protein Science Assay Technologies Biophysics SPR Safety Pharmacology Screening Services Key Instruments

Oncology

PDX CDX Orthotopic Models Syngeneic Models Humanized Mouse Models CAR-T and CAR-NK Mouse Models In Vitro Assays

Pharmacology

Immunology Inflammation Metabolic NASH Respiratory Neuroscience

Biologics

Synthetic Antibody Animal-Based Antibody Discovery Platform Systematic Antibody Discovery Service

Join our Webinar

Accelerating PROTACs Drug Discovery with One-Stop TPD Solutions: This webinar discusses high-throughput screening for protein-targeting compounds and showcases our TPD platform. It also highlights our chemistry synthesis service for PROTACs drug discovery.

Date: June 14 | 10am ET | 7am PT | 4pm CET | 10pm CST

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